Windows 10 - Cursor can't click on other windows

So recently I've had this problem on my personal Windows 10 laptop where the mouse cursor still moves perfectly fine but it only seems to respond to clicks within one process/window (and it's not always the same process), almost as if it's getting locked in . The best way to describe it is to imagine a modal window where your cursor works perfectly within that modal window but you can't click on anything outside of that modal window and the cursor won't change/react to anything outside of that window, either. Now take that same behavior and just imagine it's a browser or maybe Windows Explorer

Question by jhilgeman on Super User, licensed CC BY-SA. We show a short excerpt and link to the original thread as credit.