My mouse cursor is self-clicking and flickering

My mouse cursor is behaving like mad, it's continuously self-clicking. Option of left-click appear without me clicking it and it selects on of the option from the list. Especially while browsing it automatically left-click and selects inspects elements and developers tools opens without me doing anything and flickering that is mouse cursor keeps appearing and disappearing, its been happening for last two months and its making me mad. I have tried everything from changing mouse to updating drivers to removing unnecessary programs which made it work for some days than it restarted. What can I do

Question by nish on Super User, licensed CC BY-SA. We show a short excerpt and link to the original thread as credit.