Mouse click fails and only Ctrl Alt Del brings back the functionality

I've had this issue for 2 months. I've tried a number of things but the issue still persists. The problem is that my mouse randomly don't drag, left click, right click or double click. In this situation my mouse can move and even hover (you can see its tooltip), but clicking and the other functionality won't work. So I have two choices: Press Ctrl + Alt + Delete and click on task manager and everything will be fine for some moment. ( Ctrl + Shift + ESC won't work in this situation). I have to use keyboard or touch it and after that may be my mouse functionality will back (sometimes won't). I h

Question by Amirhossein Modirkhazeni on Super User, licensed CC BY-SA. We show a short excerpt and link to the original thread as credit.